Chemical and clinical evaluation of the continuous-flow analyzer "SMAC".

“SMAC” (Sequential Multiple Analyzer plus Computer) is a high-speed computer-controlled multitest analyzer. A 20-channel prototype SMAC (glucose, urea nitrogen, creatinine, carbon dioxide content, total bilirubin, calcium, phosphorus, cholesterol, iron, uric acid, chloride, sodium, potassium, total protein, albumin, creatine kinase, alkaline phosphatase, lactate dehydrogenase, and aspartate and alanine aminotransferases) has been evaluated for: (a) method precision during within-day runs and on a day-to-day basis over a period of time; (b) method linearity over a range established on a chemical basis and related to clinical requirements, with use of both aqueous standards and protein matrix reference material; and (c) correlation of SMAC values with those obtained by the methods routinely in use in our department.